Undisclosed antiretroviral drug use in Botswana
نویسندگان
چکیده
منابع مشابه
Antiretroviral regimens in pregnancy and breast-feeding in Botswana.
BACKGROUND The most effective highly active antiretroviral therapy (HAART) to prevent mother-to-child transmission of human immunodeficiency virus type 1 (HIV-1) in pregnancy and its efficacy during breast-feeding are unknown. METHODS We randomly assigned 560 HIV-1-infected pregnant women (CD4+ count, > or = 200 cells per cubic millimeter) to receive coformulated abacavir, zidovudine, and lam...
متن کاملAntiretroviral preexposure prophylaxis for heterosexual HIV transmission in Botswana.
BACKGROUND Preexposure prophylaxis with antiretroviral agents has been shown to reduce the transmission of human immunodeficiency virus (HIV) among men who have sex with men; however, the efficacy among heterosexuals is uncertain. METHODS We randomly assigned HIV-seronegative men and women to receive either tenofovir disoproxil fumarate and emtricitabine (TDF-FTC) or matching placebo once dai...
متن کاملAntiretroviral concentrations in breast-feeding infants of women in Botswana receiving antiretroviral treatment.
BACKGROUND The magnitude of infant antiretroviral (ARV) exposure from breast milk is unknown. METHODS We measured concentrations of nevirapine, lamivudine, and zidovudine in serum and whole breast milk from human immunodeficiency virus type 1 (HIV-1)-infected women in Botswana receiving ARV treatment and serum from their uninfected, breast-feeding infants. RESULTS Twenty mother-infant pairs...
متن کاملPediatric Antiretroviral Drug Information
Members of the Working Group on Antiretroviral Therapy and Medical Management of HIV-Infected Children have developed this Pediatric Antiretroviral Drug Information Supplement. As new information becomes available, the supplement will be updated. This document contains detailed information about the different classes of antiretroviral agents, and should be used in conjunction with the Guideline...
متن کاملEmerging antiretroviral drug interactions.
With HIV-infected patients living longer and recommendations to initiate antiretrovirals (ARVs) being made earlier, the likelihood for potential drug-drug interactions between ARVs and concurrent medications used to manage co-morbid conditions will increase. In order to maximize the clinical benefit and minimize potential toxicity of ARVs and co-administered medications, it is important for cli...
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ژورنال
عنوان ژورنال: AIDS
سال: 2018
ISSN: 0269-9370
DOI: 10.1097/qad.0000000000001862